Oppenauer Oxidation
The aluminium-catalyzed hydride shift from the α-carbon of an alcohol component to the carbonyl carbon of a second component, which proceeds over a six-membered transition state, is named Meerwein-Ponndorf-Verley-Reduction (MPV) or Oppenauer Oxidation (OPP) depending on the isolated product. If aldehydes or ketones are the desired products, the reaction is viewed as the Oppenauer Oxidation.
Non-enolizable ketones with a relatively low reduction potential, such as benzophenone, can serve as the carbonyl component used as the hydride acceptor in this oxidation.
Recent Literature
Oppenauer Oxidation of Secondary Alcohols with 1,1,1-Trifluoroacetone as Hydride Acceptor
Efficient and Selective Al-Catalyzed Alcohol Oxidation via Oppenauer Chemistry
Practical Oppenauer (OPP) Oxidation of Alcohols with a Modified Aluminium Catalyst
General Transition Metal-Free Synthesis of NH-Pyrroles from Secondary Alcohols and 2-Aminoalcohols
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